Download scientific diagram | – Cnidoscolus quercifolius plant. from publication: Análise Química e Bromatológica da Forragem da Faveleira (Cnidoscolus. PDF | Objective: To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential. The Cnidoscolus quercifolius (Pohl) popularly known as “favela” or “faveleira” is a forager that is part of the native species from the caatinga.
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Moreover, a growing number of people are seeking traditional medicine for their primary health care. There was no statistically significant difference between the LME and RBME with the reference drug Eserinewhich represents a new source of bioactive compounds with potential as acetylcholinesterase inhibitor Figure 2.
In a test of toxicity against Artemia salinaconducted by Fabri et al. The methodology began with the collection and herborization of the plant material, to obtain the chemical compounds, preliminary phytochemical analysis, and extraction of the constituents of the active cnidooscolus. Hoffm presented relevant antioxidant activity and phenolic compounds in the species, suggesting that C. Preliminary Phytochemical Analysis The extracts were subjected to phytochemical screening, following the protocols described by Mattos [ 16 ].
Van De Meent, K. To analyze the significance of the differences between the samples the authors used Variance Analysis ANOVA followed by the Newman-Keuls comparison test, being considered significant.
Matos, Plantas Medicinais no Brasil: This difference in the presence and absence of certain chemical compounds of plant species may be related to factors such as age of the plant and the time of collection [ 31 ]. The importance of medicinal plants in solving the health problems of the world is gaining more and more attention. The World Health Organization WHO has recognized and recommended the dissemination of traditional cnidoscous and use of phytotherapic medicines.
Cnidoscolus quercifolius – Wikiwand
It is important to note that this method only assists in optimizing the selection querfifolius does not eliminate, under any circumstance, the in vivo tests [ 24 ]. The United States and Germany rank among the biggest consumers of natural products from Brazil. To determine the biological activities the authors conducted investigation of antioxidant and antimicrobial activities, inhibition capacity of the acetylcholinesterase enzyme, and initial assessment of toxicity of the extracts.
Despite this unique condition, there was not enough incentive to direct local preservation botanical studies [ 8 ]. Today, according to Amorozo [ 2 ], the introduction of modern medicine offers another option for health practices in ncidoscolus communities that use popular medicine. Souza [ 55 ] describes that the absence of toxicity can be an advantage for the possibility of using isolated substances in developing herbal medicines for use in humans. The in vitro antioxidant activity of the extracts was determined using the 1,1-diphenylpicrylhydrazyl DPPH method, as previously reported by Brand-Williams et al.
In the analysis of the leaves of C. Materials and Methods 2. Antimicrobial activity of the methanolic extracts of C.
Evidence-Based Complementary and Alternative Medicine. View at Google Scholar S. In the present study, the methanolic extracts of the leaf, root, and root bark of C. Almeida [ 43 ] performed an antimicrobial assay with strains of bacteria and fungi using hydroalcoholic extract of the leaves of C.
Several studies have shown the use of Artemia salina to evaluate the toxicity of extracts, of isolated and purified substances of medicinal plants [ 3151 — 54 ], thus decreasing the use of animals for experimentation. All the methanolic extracts of the faveleira cnidooscolus anticholinesterase activity. Result of inhibition of the acetylcholinesterase enzyme from methanolic extracts of C.
Tests were performed for the detection of phenols and tannins, anthocyanins and anthocyanidins, flavones, flavonols, xanthones, flavanones, chalcones and aurones, leucoanthocyanidins, catechins, steroids and triterpenoids, and saponins. The improvement of the conditions of oxidative stress by plants has been associated with phenolic compounds such as flavonoids and other polyphenols.
The authors expect to develop a new herbal product, resulting in lower production costs and that, consequently, could be commercialized in more accessible form to the population, highlighting the risk reduction of contraindication of this category of medications. Moreover, other factors such as seasonality, circadian rhythm, development, climatic factors, water availability, ultraviolet radiation, nutrients, air pollution, and altitude may influence the qiercifolius of the secondary metabolites of plants [ 32 ].
Several authors call attention to the direct dependency on this environmental resource by the populations living out of extractivist activities within the biome [ 910 ]. In the agar diffusion method, the extracts showed activity against strains of Staphylococcus and E.
One of the first AChE inhibitors used was physostigmine, an alkaloid isolated from a plant of the Leguminosae family, although this alkaloid is no longer used clinically, due to its short half-life. Quercifoliys this, Kutchan [ 33 ] reports that the secondary metabolites have a direct relationship with plants and the environment in which they live; therefore, their synthesis is often affected by environmental conditions.
Cnidoscolus quercifolius – Useful Tropical Plants
Spreading across an area of approximately thousand square km, the caatinga, an exclusively Brazilian biome, is also one of the most endangered areas in the planet. Preliminary phytochemical analysis of C.
Ahmad and Beg [ 44 ] believe that the antimicrobial effect of vegetal quercifoluis is largely due to the presence of flavonoids in their composition, thus corroborating the results found for the C.
The caatingaan exclusively Brazilian biome, is one of the most endangered vegetation systems in the planet.
View at Google Scholar U. Advanced Search Users Online: After performing the test to evaluate the antioxidant potential of extracts of C.
The use of less complex animal organisms, as is the case of Artemia salinacan be done to evaluate the toxicity of bioactive compounds, besides being a simple, fast, and low-cost test.
Currently, this practice constitutes an amount of internalized knowledge shared among multiple users or in more traditional communities [ 1 ]. View at Google Scholar J. View at Google Scholar L.
This document aims to ensure secure access to phytotherapic remedies, considering traditional knowledge on medicinal plants, as well as promote research and encourage the development of technology and innovation, stimulating the use of medicinal plants in different stages of the production chain, ultimately fostering the sustainable use of biodiversity.
As far as we know, there are no data in the literature showing the antioxidant activity of samples of C. However, other species of the genus Cnidoscolus showed the presence of alkaloids [ 28 — 30 ].
Table 2 shows the results of antimicrobial activity of methanolic extracts of C. Therefore, the root bark extract of Cnidoscolus quercifolius has a possibility of use for anticarcinogenic therapies. Standing out among these auspicious outcomes are the antioxidant effects, the bactericidal and fungicidal potential, and the inhibitory effect against the acetylcholinesterase enzyme in two extracts tested, which showed no significant difference when compared with the reference drug.
Thus, the antioxidant therapies used in a large number of illnesses related to the generation of free radicals, such as cancer, aging, atherosclerosis, ischemia, inflammation, and neurodegenerative diseases, seem to be promising [ 35 ].